Patulin
Monitoring patulin is an important aspect of food safety, as this mycotoxin, produced primarily by Aspergillus and Penicillium species, commonly occurs in rotting or damaged apples. Although patulin is not considered highly toxic, studies have shown it exhibits genotoxic properties, indicating potential mutagenic and carcinogenic effects. Its presence in apple products also serves as a key indicator of raw material quality, reflecting the condition of apples used in food production.
Patulin contamination is most frequently detected in apple-derived products, including apple juice, apple sauce, apple puree, apple cider, and baby foods containing apple ingredients. Improper storage, processing, or the use of damaged or mouldy fruit increases the risk of patulin formation, making vigilance essential throughout the production chain. Even low levels of contamination can compromise product safety, particularly for vulnerable populations such as young children.
To protect consumers, many countries have established strict regulatory limits for patulin in apple products. The European Union, for example, set maximum allowable levels in 2003: 50 ppb for fruit juice, spirits, and apple cider; 25 ppb for solid apple products intended for immediate consumption; and 10 ppb for baby food and apple-based products for young children. Compliance with these limits requires routine testing and careful quality control throughout production and processing.

Detecting patulin presents technical challenges due to its typically low concentrations and potential interference from other components in complex food matrices. Advanced analytical methods are therefore critical for accurate detection. EASIMIP™ PATULIN uses molecularly imprinted polymer (MIP) technology to provide a highly specific, sensitive, and rapid detection method. This process involves binding patulin to MIP columns, followed by washing to remove impurities and elution for HPLC analysis. The method enhances purification and concentration of the toxin, yielding clearer and more reliable chromatograms. Crystalline patulin standards and pectinase are also available to further support precise analysis.
Regular monitoring of patulin offers several important benefits. It protects consumers by identifying and quantifying contamination, ensuring apple-based products are safe for consumption. It supports regulatory compliance, helping manufacturers meet EU and other international safety standards. It also maintains product quality and integrity by preventing contaminated goods from entering the market. By employing MIP technology combined with HPLC, producers gain a reliable, sensitive, and efficient method for patulin detection in complex matrices.
In conclusion, monitoring patulin is essential for safeguarding consumer health, ensuring adherence to food safety regulations, and maintaining the quality of apple products. Utilising advanced detection technologies and rigorous quality control procedures allows manufacturers to accurately identify and manage patulin contamination. This proactive approach not only upholds food safety standards but also reinforces consumer trust in apple-based products.

Product Portfolio
Ordering Information
| Ref | Description | Number of Tests/Amount | |
|---|---|---|---|
| TC-QP2100-50 | QualiT Pure™ Multi-Ergot Alkaloid MS | 50 Columns (Syringe Format) | |
| TC-QP1000-50 | QualiT Pure™ Multi-Mycotoxin | 50 Columns (Syringe Format) | |
| TC-QP1100-50 | QualiT Pure™ Multi-tox MS | 50 Columns (Syringe Format) | |
| RBRP250 / RBRP250B | EASIMIP™ PATULIN | RBRP250 : 10 Columns (3mL Format) RBRP250B : 50 Columns (3mL Format) |
